First time plating a rhythm game for me! And boy did I struggle. Iwas never clear on what beat I was supposed to click. Maybe make them in a different colour in the top row, that would take the guessing out of it? 
But apart from utterly failing (I never got more than 31% on the first level) I really anjoyed the challenge and the MUSIC! Oh and the microbes bouncing into each other? Fab! Maybe I just enjoyed that too much to care about the rhythm ;)

Awesome game!

• Great main menu! Very cool to have buttons for the music, github, etc.
• It could be fun to mix up the rhythm during a song, but it needs to be synched up.
• There is a function getCurrentTime() you can use to get the time of the music to help synch and trigger things.
• Cool transition wipe effect!
• The bell sound is really rough but I'm sure you can fix that easily.
• While you are fixing the bell sound, the sound when you click to the next message like in the tutorial is also a bit harsh. With Zzfx sometimes you need to try a few times to get a good sound. You can also just use a wave or mp3 sample if you have one. All the sounds here could use some tweaking, with a music based game you really need to try to make the sound effects jive with the music. You could even use different sounds depending on the song.

Great job, the procedural graphics are an awesome touch. the gameplay is simple but I cant tell if i'm doing a good job or not until the end. Awesome job with the tutorial level and UI systems, they are really clean and well implemented. I found I can get a much higher score by just spamming the spacebar as it seems I never lost progress on anything by clicking on the wrong beat. Awesome work.

I really like the animation! This is fun!

a very unique implementation for the rhythm genre. good job

Rhythm Heaven fan here, happy to see one of my favourite minigame here

Rhythm games are my favorites, and I really enjoyed this one, always trying to get 100%