Yes, you have to get the entire game folder out of the zip/rar, then you can run the game.exe from that unzipped folder normally.
Daddy Hyperion
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That's not quite how it works. After you progress past a certain point, newer scripts that weren't available in the older version will no longer trigger if you load that save file in a more recent version, which can potentially cause bugs, like certain characters or objects not showing up in places they should, which then can result in quests getting bugged. I can't tell you for sure how save files from 0.18 will do in (I assume) 0.22. You might get lucky, or you might not. Generally speaking, the less progress you've made in a save file, the less likely it is to cause problems in newer versions, since Spedumon normally doesn't change older areas of the game anymore.
1. Finish each repeatable Quest Guild quest in Piratetown at least once (all 9 of them), then talk to Buba, he's gonna tell you to go see Vulfox in the guild lounge.
2. After you spent a night at the Paradino hotel, talk to the bear at the pool outside.
3. Finish each repeatable Quest Guild quest in Paradino at least once (all 9 of them), then talk to Rexardo in the guild lounge.
If you got any more questions, check out the walkthrough.
Not in the menu directly, but when you start a new game, you're asked whether you wanna play the game, or check the rewatch house directly, with everything already unlocked. That's a feature from all the way back to the beginning of the game's development, when importing save files between updates would cause bugs, so that way people didn't have to start from scratch every single month just to see the latest smut additions. By now it's usually save to use older save files in later updates (if the versions aren't too far apart), but Spedumon doesn't wanna mess with the game's code anymore, so the gallery's still there right at the start.
After you hand him the guestbook, he appears in Bangers Club in Gloomy Forest, then at the beach. You need to tell him he's gay every time. After the third encounter, there's a random chance for him to appear in the Shiptown harbor restroom. Just leave and re-enter until there's a pink "4" over the right stall, then enter the one in the middle. After you boned him there, you can find him in the final call in the Pine Island prison. After watching the event there, talk to him again upstairs to finish the quest.
It's impressive that you went through all that trouble, but I'm afraid, sometimes RNGsus simply hates you. One time, I was farming the Fire Dungeon for SIX HOURS just to get one measly pair of Molten Greaves from the Lava Golems. I had multiple instances like this, but Spedu told me every time that the drop rates were correct. About the other thing you said, where exactly does it state that you can get only one item of that type per battle? Just because there's not a specific number next to the items on the loot sheets doesn't mean that you can get only one of them at a time.
You can either do the ACT commands "Alpha Remark! - Sit! - Beg!" three times in that exact order, or you can simply open your inventory during the fight and use the Mid-sized Buttplug. Both options will cause Wulfrick to end the fight.
Alternatively, you can bring Wulfrick's HP down to zero by actually fighting him. In that case you need a dagger, so you can keep using skills to ignore Wulfrick's defense stats. Using the "Alpha Remark!" ACT also keeps him from attacking you for two turns, so you can just keep doing that, and use TP gain to refill. However, Wulfrick's got 9999 HP, and at this point in the game, that fight will take you at least 40 minutes, and you don't get anything extra for actually defeating him. For more questions, you can check out the walkthrough.
Not sure what you mean by "characters list", but there is a walkthrough. Scroll down, and you'll also find links to all the different items in the game.
You need to finish each repeatable Quest Guild quest in Piratetown at least once (all nine of them, you'll need the golden badge for the 3-star quests). Then Buba will ask you to talk to Vulfox in the guild lounge. You can check the walkthrough for more details. Sword is the leader of the royal knights you met in Safen at the beginning of the game. So far, there's no use for the key yet, both in the public and the Patreon version.
0.21.1 is the most recent public version of the game. If you're playing that, you've already reached the end with Richtor's fight. If you wanna support Spedumon on Patreon, the latest version there is 0.81 (the Patreon version has a different numbering system than the public version, it's not 60 versions behind). Otherwise you gotta wait til November for the next public update.
In order to keep your save files, you must copy the entire "save" folder within your current game's folder (which is inside the "www" folder), and use that to replace the one in the updated version.
It's in the third room of the second level of the Deep Mines. You can check the walkthrough for more details. 
The map plus fast travel is an ingame item you get once you reach Shiptown. You have to "use" it in your inventory in the "Key Usables" section. The rest is standard RPGMaker controls: Arrow Keys or the numpad for moving up, down, left and right, Enter or Spacebar to select/interact with stuff, Shift to run/walk and Ctrl to hide/unhide text boxes, F4 for fullscreen, Esc for the menu.
They can all be found in the chests on the third floor. Each room gives you one specific piece, so just savescum in front of each chest. There is no head piece, but there is a hand piece you're also missing. For more info, you can check the walkthrough
The two doors are events at the fire- and water dungeon. To unlock them, you must finish each dungeon at least thrice, and collect the loot from the chests in Rubyro's/Saphura's throne rooms every time. Once you got the full armor set of one god, you get their event. Don't worry, the armor chests aren't random, so you only have to loot them three times. For the last four pixel animations: You need to defeat Shaun in the pirate hidehout by making him horny. To do that, you need to defeat Klaus and Dule Dile during his battle first, so he's there by himself, and then use the acts to horn him up. Then, when you leave the area, you get a cutscene where Shaun bones either Dule Dile or Klaus, which one is random, and each one of them got a pixel animation of their own. For the third one you need the gold badge, so you can accept the quest guild quest to defeat Captain Hogger in Piratetown. After you've done that, you can just talk to him to get his scene. The last one is the Demanding Foreman. Just talk to him in the Paradino mines after you defeat Richtor. You can check the walkthrough for more details.
