The Jam has a format requirement so they should all be falling in the same format generally. If something is a pamphlet, folding it might be considered for an accompanying print, but things following the guidelines most specifically will get primary consideration.
"my judgement is that as long as its not taking up more paper than the rules permit then its cool if you fold it in a different way. So a trifold or (if you want to get wild) 8 A6 pages is totally cool. I guess you could also do 2 A4 pages if you wanted but that seems boring." https://itch.io/jam/appx-n-jam/topic/5057591/layout-question
Dank Dungeon said that as long as the total area is the same it doesn't matter if it is has a different layout.