Can I create Google Chrome into a .zip file and then publish it on itch.io?

No, that would be piracy. Also, what does that have to do with the title of your topic?

1. Does this happen with every game? Or just one particular project? If it happens with every game, it may be a problem with your computer and we will need more information to determine the source of the issue. If it only happens with one particular project, the game may be buggy and I would comment on the creator's page to let them know.

2. Why would you want to upload Chrome?