It will just crash again on-save, I've confirmed that much.
As for when it happens, it seems to crash at the very end of the save animation- if I were to extrapolate from my layperson intuition of the error code, something in the slowdown effect might have caused an error to happen while saving and corrupted the save file, which would cause another crash on load attempt. That's my theory, anyway. Whatever's causing it, it's consistent between both versions of the game that I have. It's odd because I remember having played without much issue in the past.