Hey there, I suggest using https://itch.io/docs/butler/ to upload your game! With it, you can upload as much as 32GB.
It'll let you push patches by uploading only what's changed, and it'll let your players use keep the game up-to-date via https://itch.io/app easily.
We have a solid CDN as of a few days ago, so all those mirrors shouldn't be needed :)