I think Windows 10 has the tendency to simply block single .exe files that were downloaded from the internet. I had the same issue when I tried exporting my own Game Maker 1.4 projects. They worked fine on my computer, but as soon as I uploaded and re-downloaded them, Windows Defender would block them. Choosing a .zip file instead of a single .exe program in Game Maker's "Create Application" options solved that issue for me. Win 10 seems to have less of a problem if the .exe file is inside a directory with other files.
Eeyup, it works for me now! Windows Defender doesn't seem to care as long as the .exe is in a .zip file first...
Played your game twice now and I'm pretty sure I still don't understand most of it, but I liked the overall silliness. Some sounds would have been nice, even just some "beatboxed" sound effects like you did in one of your tweets...I think they would even suit the aesthetic pretty well!