Art: Outer panels are all really nice, inner spread is less appealing overall, though the map icons are nice.
Writing: Good concept, as long as everyone in the group is both okay with it and capable of roleplaying this kind of thing without being creepy about it. The writing is decent overall. Clear enough, a little bit of character development. Maybe more explanation needed of Iris's ultimate ambitions? Is it just to make ever-more-irresistible nymphs to make more money for her club? I feel like I'd want to have her running a honeypot spy network or blackmailing corporate execs or deploying robot mistresses to manipulate politicians. Depending on the PCs' preferences, might be too gendered... where are Satyrs? Some typos in the menu: pinnaple, whine.
Game Design: Everything works, I think. If I'm going to quibble about anything, it seems highly unlikely that anyone's going to find the password on the inside of the cat's collar because what reason would they have for removing it?
Theme: Aside from naming the sexbots "nymphs" there's not a whole lot that's mythical here. It's not a stretch or anything, you did the theme, but it's only integrated in a superficial way.
Layout: Using directly-connected location text boxes instead the usual map-and-key saves space, but is the reason the interior spread isn't as visually interesting as the outside. I'm not sure what you did with the Nymph/Security stat boxes is the best idea. Maybe put all those in one place and assign them to locations with an icon system like you did with the doors/stairs/corridors, instead of the dotted lines.
Utility: I see no serious barriers to just dropping this into a campaign and going.
Favorability: I think it's good. Wouldn't use it because when I'm roleplaying these days I'm usually running games for my 13 year-old son and his friends. If I did run it, I'd work it into a bigger plot about a spy ring seducing VIPs.