Are you on Ubuntu?
I'm not sure if this is related to the self-patcher not working as it should. We haven't really made any major changes to the game besides that.
The missing music and SFX is interesting though. The sound system probably crashes and anything you do in the game causes problems because of that, since most UI elements play sound when you interact with them. Will try to figure out why this happens.
When the updater works as intended, you're supposed to use that as an executable every time you open the game so you always have the newest version. :)