This happened to me too! I found that if I fullscreened a few times, the problem fixed itself. Hope this helps. :)
It sadly didnt work😔
I have updated the game with a fix that might potentially fix the issue. Maybe you could try again and let me know if it helps!
It didn't work sadly... Its a good game, don't get me wrong, I think its a problem with the interactive sprites.
Are you running it through the itch.io app by any chance? Serenitrove currently only supports browser play and won’t work if downloaded through the app.
I'm on web