Howdy!
Sorry to hear that the game isn't working properly for you. Here's some info that might help!
To clarify some of the 'Preferences' options:
- The 'Filter' option disables planets based on kinks found there, so the options to travel there become inaccessible when you're on the bridge of your ship.
- The 'Warnings' option adds warnings to planets hosting niche content when set to 'Low' and all planets when set to 'High'. The latter also adds some warnings to buttons that lead to niche content as well. Please keep in mind that the planet warning only triggers the first time you visit, and continuing past the warning disables it for next time. This option is still work-in-progress, and will be significantly more robust once the game is further in development.
- The 'Flagging' option adds a brief summary to the location buttons when you're on the bridge of your ship.
To clarify the mutation and kink stuff:
- There is a bug in Build 167 where having your mutations removed breaks the mutation blocklist. If you have a save from before 167 BugFix 1, please import it to the current build of the game and go through the mutation removal machine on your ship to reset your mutations, possible mutations, and blocked mutations.
- The 'Kink blocklist' is just for kinks that your player character can develop if you push them into the same content over and over again. There isn't a way to remove Kinks you already have yet, but it'll be a feature at some point.
- You can buy the 'Gene Profiler' at the 'Shipyard' location to pick and choose which mutations to keep and which ones to get rid of.
I was unable to replicate the Preferences settings changing after a few turns, beyond reloading or restarting the game. If you happen to encounter this again, please let me know exactly what you were doing in-game when it happened, so I can investigate further.
Hopefully this helped. Thanks for playing!