Overall I love the concept - theme is great and it's super creepy. If I were to run it, I would definitely focus the Dupli-Skin marketing around the product being synthetically grown 100% ethical skin, to enhance the payoff when the players reach the den. Both NPC and room descriptions were super evocative, and would be easy to run at the table in that sense - though tracking NPC movements may be a bit complicated. I would like to see an NPC to be keen on offering a free sample - or I would try to manufacture a situation where a pc needs to get Dupli-Skinned to save their life (just to make use of your infection table). I would also love to see you play up the horror on the events table. Rather than just npcs changing locations have them doing something at the same time (like farm staff transporting a garbage bin filled with skinless corpses for disposal).
It was a really enjoyable read, and look forward to running it at some point :)