Cool concept. I see two bugs. 1.) The lock dice mechanic don't work. It will still roll even if locked. 2.) The dice upgrade "unlock constipuateasjfk" - I forgot the name - is gone after losing.
In terms of design, I see no reason why we need to click the score handlers at left side, it's time consuming and can potentially waste "chance" pts if mistakenly chose a condition that was not met. I think the score should be given automatically after rolling the die.
If you are open to suggestions, simplify it in order for players understand easily and to be consistent to the flow: to roll these die. This can be done by removing "chances" and let them focus on "rerolls" and score multipliers from the rules. The format of scoring would be (total die points x multipliers) for simplicity.
Example: if the die are 3+3+3+1+6 = 16 Points and the scorer detects "3 of a kind" which grants x12 multipler (for example) then the total score in that turn is 192.