Hpw much memory? 16 gigs of RAM, and I'm not using a VM. I'm actually using Linux.
I dualboot Linux with Windows. I have two SSDs, one for each. Fedora can read my Windows drive, so I basically use it as extra storage since I barely touch Windows. That's where I store all my Renpy games, as well as where I run them from.
I'm not sure what you mean by running Wine under Windows. Renpy detects Windows 8, isn't that what Wine is supposed to do? I suppose I could log in to Windows and test it out.