
I may have spent a fair amount of time practicing this game. Most of the time I can get to around level 11-12. On really good runs when I'm in the zone, well, there's my high score so far.
Some tips for those that want to go higher.
First thing, use control + mousewheel to set your browser's zoom higher(mine works best at 190%). It's not as good as fullscreen(pretty please dev?), but the larger your screen, the less likely you will have mis-clicks, which is especially important at the higher levels.
Second, when examining a board, I prioritize trying and identify a 2x2 block that has 3 of the same color. If possible, find one that has a 4th block of the same color directly adjacent to your 2x2 block. If you have that setup, for all colors but two(purple and green), you can get a match by clicking only 1 to 3 times on your 2x2 block(depending on orientation. See below for an example.

It's a bit hard to see, but I've got my curser over a block of three, and then with only 1 adjacent block of the same color, I can clear a match by just clicking where I am at. Greens and purples are also very trivial as long as I make an L shape first, because then I just need to move over 1 space and then click, depending on if I need a block or a line.
This is of course by no means a hard and fast rule. It's just what I look for. If you happen to spot one of the other 3 pink blocks, or the teal blocks, or the green square that's already set up to complete, go for that first.
I also personally don't go for the double combo to clear all on the board, unless I have 2 down arrows that are by the bottom. For colors, you need to clear a minimum of 8 blocks in order the pull it off, which already lowers how many other blocks you are clearing. It is also extremely easy to accidentally match something else between your first and second clear. If you can spot it, go for it, but I personally prefer to focus on getting volume of clears rather than specific colors.
As for the theming, tbh, it pushes all of my buttons. A hot(in my mind anyway) and powerful villainess? Bondage? Resistance from the victim? A bad end? All of it yes please. I would absolutely love to see more of Dr. Brainlick in the future if that is able to be arranged. If not, that's fine too, I am totally happy with what we have here.
Hands down the best thing to come out of this jam, and I will definitely be watching out for more from this dev.