alright here is the official strategy guide:

play a few junk rounds to fill your inventory with 1s, the inventory will carry over between games. next through all your 1s near the cannons, and add as many twos and fours as you can, if an enemy comes pick up one of your ones and kill it, through out threes and fives if can but don't worry about it if you cant,  lastly if you don't have an IQ of over 300 and cant understand Rick and Morty don't even bother playing your too stupid.

(btw High Score 200)

ONLY 1 SHOOTS is a 2d math-strategy, where you should repel attacks with your attention and counting skills.

divide et impera.

HOW TO PLAY:

Use [WASD] to move, [E] to interact with guns and math-blocks, [Q] to throw number away from your inventory.

ATTENTION:

When you interact with the adder you should know some "math" rules of it. if you put 2 and 3 inside it you get 5, but if you put 2 and 4 you get 1 (6-5), so sum just overflows to 1.