I like how streamlined this is - easy and intuitive, though a certain amount of shared 'language' of assumptions is necessary to make it shine. 

That's not a criticism, I'm a big fan of games that trust players to leverage their experiences and expectations, shared or otherwise. 

Hacking Fuego to different settings would be extremely easy. Add magic, tech, romance, and/or giant stumbling robot suits with lasers and janky gyros. 

My only recommendation would be to consider adding a mechanic that allows a Protagonist to cede victory to another Protagonist in return for some kind of boon. Turn that opposed d12 roll into an interesting roleplay decision!