Honestly, I can't really get into this game. It feels more like a game of pure chance than having anything to do with skill; 

though I will concede that there are some situations that require a bit of thinking, for exemple, how to get the biggest combo if there are multiple copies of multiple cards in close numerical succesion, but other than that, it is just kind of click and point I find.  I would love to give constructive critisism and propose possible solutions to this ploblem, but I sadly feel like it is just inherent to a card game like this.  

It is not all bad of course, I like the roguelike part a great deal (though I would suggest making upgrades progressively more expensive after each one, I don't know if this is feasible of course) and I always like card games that use an actual 52 card playing-card deck. 

I think this has potential and I encourage the dev to keep going!

I hope this helps a little bit :)