During combat, I've consistently run into a targeting bug. It might be exclusive to the Zheng mod (built for an earlier version?), but if so, I've run into it multiple times even before the current update.  It only happens when I try to aim at a target that's on hard cover with the charged D/D 288.

As seen here, it brings up the target selection window on mouseover instead of on click, and that paradoxically makes it impossible to target anything, because when I try to select the target, it goes away then comes back up when I mouse over the target again.  If I try to click on the target, it just tells me I've selected nothing and if I'm sure I want to proceed.

Again, this could be because the Zheng mod is old and needs a compatibility update, but if it's something to do with superheavy melee weapons in general, it'd be something to look at.