I just started the game and noticed one game-breaking issue right at the beginning.
When trying to view the requirements for the final achievement (No. 70, counting from left to right, from top to bottom, following No. 69 "Vampires revenge. Clear out all 10 battlefield rounds."), the game crashes while displaying the following message:
>>>
Script 'Jacob Quest Achievements' line 440: NoMethodError occurred.
Please send error report to Spacefarer Games.
undefined method `size' for nil:NilClass
<<<
Patch_rom_003 had been copied into the game's folder beforehand. I thought I should report this issue right away, since I don't know if it will prevent me from claiming the trophy later when its conditions are met.
Edit: It seems the trophies are claimed automatically, but it would still be great being able to check No. 70's requirements at all and without the game crashing.