The BBC Mini Series "Good Omens" (itself based on Neil Gaiman and Terry Prachett's book of the same name) contains exactly the kind of absurd/fantastic storyline and humor that make for a great time in a TTRPG. After watching, I was especially left interested in Agnes Nutter's prohecies, so I decided to create a game based on averting a catastrophic event with the support of an unlikely friend in an opposing faction, helped along by prophecies from an ancestor - except this one is genre-agnostic! Want to play in a grim WWI setting trying to figure out a truce? You go for it. Want to play in a whacky retro sci-fi setting in which the world is about to be consumed by an alien entity? There's nothing stopping you. Especially not me; in fact, I will point you right this way.
Hope you enjoy: