I gave a try to the game and i loved it so far, i had two small settlements that weren't even half-way done and then my game started to slowdown and freeze really bad, at first it just froze when i tried to speed it up, but at the end i wasnt able to play even in normal speed.
Specs:
Operating System
Windows 7 Home Basic 64-bit SP1
CPU
AMD A4-4000
Richland 32nm Technology
RAM
8,00GB Single-Channel DDR3 @ 672MHz (9-9-9-24)
Motherboard
MSI A68HM-E33 V2 (MS-7721) (P0)
Graphics
768MB ATI AMD Radeon HD 7480D (MSI)
Edit: This is all i made so far. 3 towns, but i haven't built anything yet in the third one.
Edit 2: I noticed that the game won't go past 150-250mb of memory, when it could easily use up to 1gb to run smoothly.