When the game is set to exact resolution of the screen (in my case 1920x1080) and application scalling is set to something bigger than 100% the game does not fit the screen. If on top of that, the game is in fullscreen the hitboxes on UI do not work no matter where on the screen you click. Non of other games I own are affected by this.
Repro rate: 100%
Workaround: Go to your desktop. Right click empty space. Select "Display Settings". Change the size from recommended to 100%.
Expected fix: The game should ignore this scaling.