The same way as any other game? Package it in a Zip archive and let players know that they need Python to run it. Or else you can use tools like pyInstaller and cx_Freeze to make an executable that contains the Python interpreter and your game.
A browser game made in Python? Okay. It still needs to have an index.html file like any other. Just put it all in a zip archive and upload it. Set the type of project to HTML5, and tick the checkbox that says "this file will be played in the browser" next to your upload. Hope this helps!
I didn't get any notifications because you deleted a post. If you don't have an index.html and you don't know how to make one, then I don't see how your game is supposed to run in the browser. Maybe just offer it for download.