I think it is possible, as long as you follow the trends/styles:
- Super Mario
- Sonic
- Furry Porn
- Minecraft
- FNAF
- Backrooms
- homo or trans , or both
- Zombie FPS
- Disney/Marvel and what not
edit: if you make anything pornographic, it should even sell in GameDev communities. Less marketing efforts required. People actually search for that stuff. Anything else you have to spam the entire internet to get a handful of players... over the period of 10 years, lol