So far, this has been a really interesting experience, and I'm excited to see the full game!
The one gripe that I really have with it is the plant enemies. The rooted status is simply too strong. I've had two separate runs that ended because I essentially got stunlocked in one place by a plant enemy. Even though I had some ranged cards, there wasn't a way to effectively fight back against the plants because they weren't in line of sight.
But, assuming that it isn't a problem in the full game, I have no complaints. This is really cool! =)