Hello sully,
Yes, it's possible: The first room in the demo is more or less an example of this: the background is illuminated, and the interior is dark with lights. You can add a Direct Light of any color (like white - for a neautral color) in the background to illuminate the exterior environment, with the depth of light below the depth of the "dark area". Ideally, the dark area will need occluders/shadows for walls to block internal light from passing out, like below (shadows are optional):

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