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You have Pico8 , PQ93 and TIC-80 just with "Game Boy" alike...
To move on to other genres you have tons of options , from GoDot, to RPG Maker, and even trying to use one of those obscure engines (there's one for making zelda games and other one for making warcraft 1 and 2 type games)

They are not the same in terms of ease-of-use.