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How do I give the Shopkeeper medicine? :(

If you are talking about the quest where you hand them in, talk to him and ask him about the jobs, on the quest screen, select end follow by yes to hand the quest items in to him.

Check the study option back at home, you can also look for the help from lizardman priestess. If you have spectral sirup, just visit the shop and there should be an option to give it to him.