Interesting thought. Yeah, if they think what they do is working, they might just do more, because it looks like it is working. But itch is such a honey pot. I doubt they would be discouraged, and instead just change method. Maybe some forms of spamming can be deterred, like you say, it is the stuff that does not even reach me.
The "fake download button scammer" that is at it every week (now with different method), you could communicate with. He replies to comments sometimes ;-)
Edit: the reported games are all gone in the meantime.
Since there is no scam/malware option, I am unsure what category I should report or which info I should give to make work easier. Or what I should not write in the box lest I make it complicated. I think two of the reports got quarantined rather quickly, making me think stuff was overworked and could not look at the rest yet.