I don't think this is a bug, in a sense that there's some "no running zone" (especially interior). If you think you're encountering a zone where you should be able to run, mail me with the details,
Same with the item bug, mail me the exact detail and the expected result so I can exactly understand what's going on.
As for the hospital and the "game over" state, I pondered a lot on that topic.and I ultimately decided against it because I think this doesn't flow well in the game. And especially in ABDL games, I think the "fail state" shouldn't be a "desirable" state because this is the antithesis of gaming. Hence, the game provide you with "events" where you can play through rather that a fail state where a lot of players would intentionnaly fail the game. I hope this reply to your question.