I'm running a Schiit Modi 2 DAC and getting no sound in the game, tried restarting a couple of times, disabling all other audio devices, etc. Changing my sound level (or testing the device) through the Windows 10 Playback Devices confirms that the sound works otherwise. No problems in other applications or games.
Probably irrelevant to the problem at hand but I have an RX 270 and the graphics performance is also very choppy at high settings (2560x1600).