Liked the binding of isaac style room layout! I did something similar in my submission.
Shooting was both fun and challenging. I couldn't get to the ending (if there is one) because I kept getting stuck with the doors bug, I gave it a few tries and got to room 4 I think (so a highscore of 3) and then lost to the time!
I would've liked for the player to have a bit more time than 1 minute, sometimes it felt like I was going as fast as I could and still lost.
I think besides those 2 issues the game is great! the curses add spice to it, the enemies are satisfying to kill, it would be awesome if it had a bit of particles or knockback when shots land, but as it stands, it's a pretty solid entry!