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Settings do not work at all. (prefer to play in windowed mode to reduce workload on graphics-card.)

Weird - Even after hitting the full screen toggle and clicking apply? What platform if you don't mind me asking?

Full screen toggle doesn't respond to anything,
Neither does resolution.

running on win 7

Ah, too bad. Must be bugged. You can try passing the executable arguments to change the resolution, but I don't have another solution unfortunately.