I figured one and another out in the meantime.
Some things that I didn't notice before:
1+2+7. At the center of the screen there is a little tetragonal dot. When I put it on sme item, like the reource table or a freshly killed beast, then a yellow text appears at the bottom left of the screen, telling me that I can interact.
For your information, I'm playing on a 1920x1080 monitor, with a nvidia 2070 RTX card. I have the issue both in Fullscreen and in Fullscreen Windowed modes. I didn't find any option in the settings to rescale the resolution.
3. For instance, I walk up to the table just mentioned, and stand facing it, seeing the MC from behind. Then I turn the camera, and I press 'W' to start walking away (I should say "running"). Then she doesn't turn around to walk away from the camera, but stays put. I need to use 'A', 'S' or 'D' first.
When I am facing the table, and I push 'S', then she walks away from the table backward (as it ought to be ofc). So I suspect that the issue is in the design of the response to those keys.
4. There are two women. One is indeed Isabell, dressed in white. But next to the waystone there is a naked woman named "Survivor", with a 100/100 health bar and a skull symbol. And yeah, considering that I die so often, I think that I died recently before that. But at the moment, she is still there.
5. I did find that the PrintScreen key can be remapped. But can I detach that key altogether, instead of mapping it onto another one?
I'm asking because I'd like to have the screenshots move to my regular screenshot folder instead of the one dictated by the game.