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Just adding up, I got this same 3rd bug where u couldn't talk to anyone, however, since I could still do the quests, I decided to keep moving forward, then I reached the quest from the ship engineer of ensis, where you have to go to 1 floor below and kill that purple humanoid experiment to get the corrupted heart, however, after killing him i spotted that the floor below that one, that were on the previous version locked with a chained red cube like thing, was open, so i tried to go below which failed and triggered an array out of bounds expection, so i gave up and tried to climb up the stair to deliver the quest, but this also triggered the same exception, I found myself locked there and tried to load the game again, which didn't work and triggered the same error and also keep loading forever

I released a hotfix not long ago, so the first bug you mentioned should be fixed if you update. 

Yeah, there isn't anything below that area. Not sure why it didn't have the stair blocker that time.