If you read the text checks you can see what they are looking at, I think you get auto raped above strength level seven with the werewolf, and oral knotting is supposed to be a bad end so avoid blowing the werewolf.
Most other characters are rather simple, but save often and enjoy exploring your options. As a general rule of thumb, if you lose to the same species three times, it's a bad end. So let's say you get defeated by a harpy three times, you'll end the game. Though there are several first try game enders.
Some characters are rather tough depending on what you're trying to do, I keep asking about getting the oral ending on the goblin but I still have trouble and I've been into it for a couple of months now.
As far as other stats really I go for endurance, agility, and perception. Endurance helps recovery during grapples, and agility helps give your attacks priority. Perception if high enough helps your scouting and allows you to see what your enemy's next move is. Charisma is helpful for certain tasks and same with magic, but strength I never get above seven. Buy gauntlets, sabatons, and a helmet early on, like your first visit to the village. Ring gags are fun.
As far as combat there's a basic explanation at the beginning when you have your first fight. I recommend getting hit the deck and seduction in particular. If you can get magic start with combat fire for ghosts. And for perks I suggest catamite for fun, cum drinker as a health support, and surveyor for scouting.
There are probably a few people out there with more detailed set ups but in my post history somewhere I submitted a link to a general guide. Have fun.