I am not sure what the creepiest art of the game is, the monstrous creatures that you created, or just the scientists with their eyes shifting. Both feel inhuman and creepy and really add to how dark the story seems.
A lot of the experiments feel really strange, especially when they made a flower out of toes, it feels like the scientists started creating things because they can without purpose. While I am not sure what he becomes at the end, it was so strange and creepy and gave me the feeling of Cronenberg movies.
Really great game, and the visuals are truly amazing and stand out from some of the horror games I played.