Are you using Win or Mac? Win7/10? Which Pixel FX version? 1.1.5.3 ? Any screenshot of the crash? There is any error output? like a dialog window or something? Please, give as much info as you can to fix the bug please.
I am using Windows 10. I am using the latest version of Pixel FX Designer (1.1.5.3). The crash occurs after double clicking on a .ppd file from the load menu in the top-left corner. Here's an image showing the log that appears when the program crashes:
Even the ones in the "examples" folder? When you load same error? Ne and save, and if you try to load error? Are you tried to run PixelFX in administrator mode? maybe there is some permission failing mm.