The save is located in APPDATA/Local/ShopSim (%appdata% brings you to APPDATA/Roaming)
If the game is not allowed to access the save, or is not allowed to access other folders and the like, Then it's likely to run into problems.
Chances are pretty high, that your game is either Not being allowed to do that, Or some program is being an overprotective pest, Like certain antivirus programs that need to chill the hell down.