I wonder if some intrepid writer-artist created a game like this for themselves and generated the Voynich manuscript that folks scramble and obsess over trying to understand at least the sketches if not as much the cyphered and perhaps nonsensical text.
I actually want to try this with some kind of Alone Among the Stars hack, and using a d6 to create doubt on rolls of one pip. I tend to prefer more open prompts for myself.