Cool! Always fun to watch people play my game. 😍 Super glad to see you picked up pretty much all the mechanics and tactics very well. Maybe the only thing you were lacking on was harnessing the power of those explosions (and dodging them by having a spot to jump to safely). With that the unidentified pills become way less scary and therefore much more of a tool to be abused to your advantage.
Seems like there is something wrong with the AI target switching after they have killed their first target. Colonel Moose gladly killed two of your crew before going into its peaceful slumber. That run got kinda screwed by "bad" items and accidental rushing deeper too fast. The game isn't still too well balanced and you really need to gather all the resources you can and also need good luck to get through (six floors in total).
The diagonal movement (which caused your accidental skip) is not possible around the corners so there needs to be a block on both sides to be able to make the diagonal move. And manoeuvring multiple characters is indeed quite janky since they don't know about each other on their pathfinding but will not be able to move past each other either. Same is true for the enemies too though so they can get themselves stuck on each other.