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Most likely you didn't have enough power to stop some event, or if you left it alone for a long time, enough agents died and were replaced that their power dropped (every time an agent dies, you lose a little bit more ability to fight than that agent was worth). Can you send me your save file? They are automatically backed up when you lose, and there's a button in the pause menu to open where saved files are located.

I tried to open my save files and it just closes the game