Yeah, got this issue as well, on Windows 10 Home 22H2/ESU for me. Only thing to do for now is temporarily disable real time protection before playing QUOD.
Dude, the author has shown us his face and is super open. The chance of him being really into going to prison in a convoluted scheme is pretty small. With that said, of course you should never trust an executable, because who says Itch won't be hacked, Daivuk won't be hacked, etc.