I love the page one art. I totally get the vibe you are going for here and I think you have accomplished it superbly. Also your language and word choice is excellent and really supports the setting. I like the Neso to N350. I am not familiar with Mud + Laser, so perhaps I'm not the best to give feedback here, but it seems like a cool system that I would enjoy from what I read.
In terms of visual design, I think everything is perfectly functional and clear, but for the purposes of the competition I think it could be developed further in terms of background, font choice, and maybe a more dynamic layout. There is a lot of content, which is fantastic and well done, but pushes it towards being a bit of a "wall of text". This might benefit from being edited down some to allow the highlights to stand out more. A picture of one of the "nymphs" would add a lot.
I think it's very clear how to run it. I would have no trouble picking this up and playing it at my table!
Great work!