It happened fairly consistently when i would enter the house and try to go up the stairs. I tried to post a screenshot but itch wouldn't let me, something about D3D crashing.
I see, it is probably being too heavy on your GPU - That house is the heaviest zone.
You can try pressing O to cycle between lower graphics settings, see if it helps. If not, perhaps play the game later...
Good luck, and my sincerest apologies.
No reason to apologize! Optimization in UE is notoriously fickle and it's a jam game, so it's not like you had a lot of time :)