Game design: The time being both the health and currency created very interesting gameplay and choices, though I feel like the 10 minutes were too long to really feel the impact of the relic choices, if the starting time was cut in half or even less, the relics could then really become important. The individual relics did feel well thought out and varied though.
Controls: Having to switch between mouse and arrow keys for every relic choice felt unwieldy and aiming was also difficult (or was that your intention?) with the arrow keys, usually the most intuitive way to control aiming in these types of games is with the mouse.
Visuals: I would've like to see some more visual feedback when hitting the enemies and triggering abilities and the environment (room) felt quite empty, the default Unity font in the UI also felt a bit out of place. On the flipside, the sprite art style looks great!
Sound: The volume of the game (at least for me) was too quiet. The sound effects were fitting and stylized well, but I would've like to see more of the game have sounds (especially the enemies, spawning and death feel very detached from the game with no sound). A generic UI clicking sound (like the one in the main menu) for the relic selection would've also been a great addition.
I don't want to be overly critical, I really liked the whole idea, these are just my unfiltered thoughts after playing the game. Good job on making a fun game for this jam :)