Oh, wow, I didn't expect someone to study the game so well. You're completely right on the pause button, I kinda knew someone was gonna unfortunately get got by that, my bad, but it was too late to fix. I'm surprised cave spiders were the toughest though. I usually tested with greed + sharpened edge, later adding precision drugs and opportunistic, maybe vampirism or flasks, so I was almost always just one tapping them. I guess with an attack-speed build like yours, high hp monsters are pretty rough.