Great gameplay loop and it's pretty addictive! I really liked the randomness to each playthrough and having to adapt to different abilities. There's a lot of variation which helps keep things interesting.
The art is good but I feel there are quite a few conflicting resolutions across the sprites and UI which takes away from the NES-feel. Tidying this up to keep things consistent would help to make this feel very polished.
Loved the wacky music, those tunes are a lot of fun to listen to!