I love love games, they are so... elegant in such a small size.
By the way, I got blocked, after a while i couldn't infect other beings and no wheels appear, but the core idea is strong.
It is simply a matter of exponential growth: over time, accumulating mutations becomes increasingly difficult, and the wheel stops turning. On the left, you see...
Ok, i had to restart the game a couple of times because the wheel didn't appear, but now I tested it. I confirm is really elegant.